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BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20240528T103000
DTEND;TZID=America/Toronto:20240528T120000
DTSTAMP:20260510T051153
CREATED:20250314T183239Z
LAST-MODIFIED:20250314T183239Z
UID:1050-1716892200-1716897600@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI/CIRC Seminar – Dr. Jennifer Chen\, Associate Professor\, Chemistry\, York University \nNanocrystals and their assemblies for sensing and imaging
URL:https://mycrbi.com/event/1050/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20240514T103000
DTEND;TZID=America/Toronto:20240514T120000
DTSTAMP:20260510T051153
CREATED:20250314T183131Z
LAST-MODIFIED:20250314T184104Z
UID:1048-1715682600-1715688000@mycrbi.com
SUMMARY:
DESCRIPTION:  \nCRBI/CIRC Seminar – Dr. Alvine Boaye Belle\, Assistant Professor\, \, Dept of Electrical Engineering & Computer Science York University \nHumanity 101 for cyber-physical systems
URL:https://mycrbi.com/event/1048/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20240425T133000
DTEND;TZID=America/Toronto:20240425T143000
DTSTAMP:20260510T051153
CREATED:20250312T184836Z
LAST-MODIFIED:20250312T184836Z
UID:985-1714051800-1714055400@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Dr. Martin Schmeing\, McGill University Thursday April 25th 2024 \nBiosynthesis and use of the most interesting polymer you didn’t know existed \nAbstract: \n \nCyanophycin is a natural product polymer with a poly-aspartate backbone and arginines linked to each Asp side chain. Used in bacteria for storage of fixed nitrogen\, carbon and energy\, long chains of cyanophycin coalesce into inert\, membrane-less granules which can occupy most of the volume of a cell. Cyanophycin has a variety of potential green industrial and biomedical applications. Cyanophycin is made by cyanophycin synthetase 1 or 2 through ATP-dependent polymerization of Asp and Arg\, or β-Asp-Arg\, respectively. It is degraded into dipeptides by specialized exo-cyanophycinases\, and these dipeptidase are hydrolyzed into free amino acids by nonspecific isoaspartyl dipeptidases. I will share highlights of our structural and functional studies of cyanophycin biosynthesis and degradation\, which led to surprising discoveries: Our structures and biochemical assays of the cyanophycin synthetase 1 revealed it to be a remarkable\, multi-domain\, multi-functional biosynthetic machine and uncovered a hidden hydrolytic active site that is crucial for rapid biosynthesis. We also showed that cyanophycin synthetase 2 can assume several elegant architectures that influence its synthetic activity. Further\, we discovered and characterized a novel\, large family of isoaspartyl dipeptidases dedicated to cyanophycin metabolism\, which allows the human pathogen Pseudomonas aeruginosa to use β-Asp-Arg as a sole carbon source\, and as good a sole nitrogen source as ammonium. Bioinformatics results underscore how common it is for bacteria to be cyanophycin producers or scavengers\, much more so than currently appreciated. 
URL:https://mycrbi.com/event/985/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20240423T103000
DTEND;TZID=America/Toronto:20240423T120000
DTSTAMP:20260510T051153
CREATED:20250314T183010Z
LAST-MODIFIED:20250314T183010Z
UID:1046-1713868200-1713873600@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI/CIRC Seminar – Dr. Sebastian Magierowski\, Associate Professor\, Dept of Electrical Engineering & Computer Science York University \nSequencing on Silicon
URL:https://mycrbi.com/event/1046/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20240409T080000
DTEND;TZID=America/Toronto:20240409T170000
DTSTAMP:20260510T051153
CREATED:20250314T182827Z
LAST-MODIFIED:20250314T182827Z
UID:1044-1712649600-1712682000@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI/CIRC Seminar – Dr. Derek Wilson\, Professor Department of Chemistry \nUnderstanding COVID vaccine efficacy on the molecular level
URL:https://mycrbi.com/event/1044/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20240326T103000
DTEND;TZID=America/Toronto:20240326T120000
DTSTAMP:20260510T051153
CREATED:20250314T182713Z
LAST-MODIFIED:20250314T182713Z
UID:1042-1711449000-1711454400@mycrbi.com
SUMMARY:
DESCRIPTION:  \nCRBI/CIRC Seminar – Dr. Pouya Rezai\, Associate Professor\, Dept. of Mechanical Engineering\, Lassonde School of Engineering \nFunctional Materials Integrated with Microfluidics for Sample Preparation and Detection of Pathogens and Contaminants in Fluids
URL:https://mycrbi.com/event/1042/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20240312T103000
DTEND;TZID=America/Toronto:20240312T120000
DTSTAMP:20260510T051153
CREATED:20250314T182601Z
LAST-MODIFIED:20250314T182601Z
UID:1040-1710239400-1710244800@mycrbi.com
SUMMARY:
DESCRIPTION:  \nCRBI/CIRC Seminar – Dr. Nima Tabatabaei\, Associate Professor Department of Mechanical Engineering York University \nHarnessing Light for Molecular-Specific Sensing and Imaging of Biological Samples
URL:https://mycrbi.com/event/1040/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20240220T103000
DTEND;TZID=America/Toronto:20240220T120000
DTSTAMP:20260510T051153
CREATED:20250314T182338Z
LAST-MODIFIED:20250314T182338Z
UID:1038-1708425000-1708430400@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI/CIRC Seminar – Dr. Ebrahim Ghafar-Zadeh\, Associate Professor\, Dept. of Electrical Engineering & Computer Science\, Lassonde School of Engineering \nElectronic Point-of-Care Diagnostics: Recent Advances and Future Prospects \nBill Kim\, Assistant Professor\, Dept. of Chemistry\, York University \nNext-generation Genome Editing: Technology and Applications
URL:https://mycrbi.com/event/1038/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20240213T103000
DTEND;TZID=America/Toronto:20240213T113000
DTSTAMP:20260510T051153
CREATED:20250314T181929Z
LAST-MODIFIED:20250314T181929Z
UID:1036-1707820200-1707823800@mycrbi.com
SUMMARY:
DESCRIPTION:  \nCRBI/CIRC Seminar – Dr. Jude Dzevela Kong\, Associate Professor\, Department of Mathematics\, York University \nHarnessing Light for Molecular-Specific Sensing and Imaging of Biological Samples
URL:https://mycrbi.com/event/1036/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20240123T103000
DTEND;TZID=America/Toronto:20240123T120000
DTSTAMP:20260510T051153
CREATED:20250314T181757Z
LAST-MODIFIED:20250314T182446Z
UID:1034-1706005800-1706011200@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI/CIRC Seminar – Dr. Jianhong Wu\, Professor Dept. of Mathematics\, York University \nIdentifying contact mixing patterns in respond to public health interventions and behavioral changes
URL:https://mycrbi.com/event/1034/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20240109T103000
DTEND;TZID=America/Toronto:20240109T120000
DTSTAMP:20260510T051153
CREATED:20250314T181613Z
LAST-MODIFIED:20250314T182415Z
UID:1032-1704796200-1704801600@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI/CIRC Seminar – \nDr. Seyed M Moghadas\, Professor\, Dept of Mathematics\, York University \nCOVID-19 Quarantine and Testing Strategies for Preventing Onward Transmission \nJason Kindrachuk\, Associate Professor\, Medical Microbiology & Infectious Diseases\, University of Manitoba \nInvestigating emerging zoonotic virus circulation and spillover at the human-wildlife interface in diverse global settings – increasing preparedness and response capacities
URL:https://mycrbi.com/event/1032/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20231218T103000
DTEND;TZID=America/Toronto:20231218T113000
DTSTAMP:20260510T051153
CREATED:20250311T151234Z
LAST-MODIFIED:20250311T151514Z
UID:983-1702895400-1702899000@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Karen C. Waldron\nDepartment of Chemistry\, Université de Montréal \nCrosslinked proteolytic enzymes for microscale proteomics applications \nProteolytic enzymes are routinely used to cleave the potentially thousands of proteins in a biological sample into smaller\, more manageable peptide fragments. This facilitates their separation and identification by nano-HPLC\, capillary electrophoresis (CE) and/or mass spectrometry (MS). This process\, called peptide mapping\, is one of the steps used in the workflow for identifying\, quantifying\, characterizing or probing the function of proteins in the vast field of proteomics\, specifically “bottom-up” proteomics. Insoluble proteolytic enzymes (i.e.\, trypsin\, chymotrypsin\, pepsin\, Lys-C\, Asp-N\, etc.) offer several benefits such as limited autolysis\, reusability and rapid digestion because high enzyme-to-substrate ratios can be used. The added advantage of adaptability to microreactor formats and microfluidic platforms comes from using glutaraldehyde (GA) to crosslink enzymes and render them insoluble instead of immobilizing them on solid-phase supports. In 2004 we reported a multi-step GA-crosslinking procedure for trypsin and compared its specific activity and peptide maps to trypsin immobilized onto GA-functionalized glass beads. The procedure was later adapted for chymotrypsin to digest nanomolar concentrations of fluorescently labelled protein substrate with peptide mapping by CE laser-induced fluorescence (LIF) detection. A GA-chymotrypsin microreactor was fabricated in a capillary column by programing reagent delivery in a CE instrument. Despite the ease in making GA-crosslinked trypsin and chymotrypsin “particles”\, their re-use for multiple digestions has been problematic. Our successes and setbacks will be discussed\, as well as our efforts to improve the robustness of the crosslinked enzymes using a Design-ofExperiments (DOE) approach to investigate the experimental parameters in our multi-step crosslinking method.
URL:https://mycrbi.com/event/983/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230307T080000
DTEND;TZID=America/Toronto:20230307T170000
DTSTAMP:20260510T051153
CREATED:20230307T124700Z
LAST-MODIFIED:20250215T150057Z
UID:853-1678176000-1678208400@mycrbi.com
SUMMARY:CRBI seminar - Philip Britz-McKibbin
DESCRIPTION:Abstract: \n  \nNew advances in analytical chemistry for large-scale epidemiological studies: Insights into nutrition and smoke exposures for global health \n  \nA suboptimal diet and tobacco smoking are two leading modifiable risk factors in chronic disease burden globally that are typically evaluated using questionnaires by epidemiologists despite being prone to bias and misreporting. This presentation will focus on new advances in mass spectrometry (MS)-based metabolomics research when coupled to capillary electrophoresis (CE) that may allow for more reliable assessment of exposures and their health impacts in large-scale epidemiological studies. A capillary electrophoresis assay for surveillance of iodine deficiency in the Canadian population will first be presented. This work revealed differences in iodine nutrition and exposures to environmental iodine uptake inhibitors in four different regions across Canada. Also\, recent developments to expand CE-MS techniques for untargeted lipid profiling when using nonaqueous conditions will be discussed. This approach was used to identify specific circulating lipids associated with omega-3 index status\, including biomonitoring changes following high-dose fish oil supplementation. Lastly\, I will present a new approach for biochemical verification of tobacco smoke exposures in various countries at different socioeconomic status in support of global health and chronic disease prevention. Stratification of fast from slower nicotine metabolizers offers a unique way to better assess the true hazards from tobacco smoking in diverse populations.
URL:https://mycrbi.com/event/crbi-seminar-philip-britz-mckibbin/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230201T100000
DTEND;TZID=America/Toronto:20230201T100000
DTSTAMP:20260510T051153
CREATED:20250314T181321Z
LAST-MODIFIED:20250314T181321Z
UID:1030-1675245600-1675245600@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Dr. Leo Chou\, Professor\, University of Toronto
URL:https://mycrbi.com/event/1030/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230118T100000
DTEND;TZID=America/Toronto:20230118T110000
DTSTAMP:20260510T051153
CREATED:20250314T181226Z
LAST-MODIFIED:20250314T181226Z
UID:1028-1674036000-1674039600@mycrbi.com
SUMMARY:
DESCRIPTION:  \nCRBI Seminar – Dr. Simchi\, Professor\, Fraunhofer Institute
URL:https://mycrbi.com/event/1028/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221212T100000
DTEND;TZID=America/Toronto:20221212T110000
DTSTAMP:20260510T051153
CREATED:20250313T183535Z
LAST-MODIFIED:20250313T183535Z
UID:1015-1670839200-1670842800@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Dr. Terry Sachlos\, Associate Professor – Teaching Stream\, York University \nNew paradigm of leukemic stem cells and how they can be targeted using differentiation therapy as novel therapeutic strategy
URL:https://mycrbi.com/event/1015/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221118T100000
DTEND;TZID=America/Toronto:20221118T110000
DTSTAMP:20260510T051153
CREATED:20250313T183420Z
LAST-MODIFIED:20250313T183420Z
UID:1013-1668765600-1668769200@mycrbi.com
SUMMARY:
DESCRIPTION:  \nCRBI Seminar – Dr. Jennilee Gavina\, Research Scientist\, Gilead \nHow can you as an analytical chemist contribute towards developing life saving medicines within the pharmaceutical industry
URL:https://mycrbi.com/event/1013/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220504T100000
DTEND;TZID=America/Toronto:20220504T110000
DTSTAMP:20260510T051153
CREATED:20250313T183239Z
LAST-MODIFIED:20250313T183239Z
UID:1011-1651658400-1651662000@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Dr. Frank Delaglio\, Professor\, University of Leicester\, UK \nExploiting NMR for Biomanufacturing needs
URL:https://mycrbi.com/event/1011/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220406T100000
DTEND;TZID=America/Toronto:20220406T110000
DTSTAMP:20260510T051153
CREATED:20250313T184611Z
LAST-MODIFIED:20250313T184611Z
UID:1018-1649239200-1649242800@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Dr. Igor Jurisica\, Medical Biophysics\, University of Toronto \nAi is not Enough: Explainable Biology for Improved Therapies \n 
URL:https://mycrbi.com/event/1018/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220302T100000
DTEND;TZID=America/Toronto:20220302T110000
DTSTAMP:20260510T051153
CREATED:20250313T182905Z
LAST-MODIFIED:20250313T182905Z
UID:1006-1646215200-1646218800@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Yulia Gerasimova\, Professor\, University of Central Florida \nNucleic acid interrogation with colorimetric and fluorescent DNA probes
URL:https://mycrbi.com/event/1006/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220202T100000
DTEND;TZID=America/Toronto:20220202T110000
DTSTAMP:20260510T051153
CREATED:20250313T182753Z
LAST-MODIFIED:20250313T182753Z
UID:1004-1643796000-1643799600@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – John Chaput\, Professor\, Chemistry University of California\, Irvine \nRedesigning the Genetic Polymers of Life
URL:https://mycrbi.com/event/1004/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220111T100000
DTEND;TZID=America/Toronto:20220111T110000
DTSTAMP:20260510T051153
CREATED:20250313T182631Z
LAST-MODIFIED:20250313T182631Z
UID:1002-1641895200-1641898800@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar -Vadim Elisseev\, IBM Research UK \nAccelerating Scientific Discovery
URL:https://mycrbi.com/event/1002/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210602T100000
DTEND;TZID=America/Toronto:20210602T110000
DTSTAMP:20260510T051153
CREATED:20250313T142437Z
LAST-MODIFIED:20250313T142437Z
UID:1000-1622628000-1622631600@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Sterhios Moschos \nUnderstanding SARS-CoV-2 airborne transmission: the role of exhaled breath
URL:https://mycrbi.com/event/1000/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210414T100000
DTEND;TZID=America/Toronto:20210414T110000
DTSTAMP:20260510T051153
CREATED:20250313T142320Z
LAST-MODIFIED:20250313T142320Z
UID:998-1618394400-1618398000@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Jeff Chan\, Professor\, Chemistry\, University of Illinois \nExpanding the Chemical Toolbox for Acoustic-based Imaging of Cancer
URL:https://mycrbi.com/event/998/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210224T100000
DTEND;TZID=America/Toronto:20210224T110000
DTSTAMP:20260510T051153
CREATED:20250313T142211Z
LAST-MODIFIED:20250313T142211Z
UID:996-1614160800-1614164400@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Chuan He \nRNA methylation in gene expression regulation
URL:https://mycrbi.com/event/996/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210217T100000
DTEND;TZID=America/Toronto:20210217T110000
DTSTAMP:20260510T051153
CREATED:20250313T142029Z
LAST-MODIFIED:20250313T142029Z
UID:994-1613556000-1613559600@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Ji-Young Young\, University of Toronto \nUnderstanding the Architecture of Stress Granule Proteome During Stress
URL:https://mycrbi.com/event/994/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210113T100000
DTEND;TZID=America/Toronto:20210113T110000
DTSTAMP:20260510T051153
CREATED:20250313T141815Z
LAST-MODIFIED:20250313T141815Z
UID:992-1610532000-1610535600@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Chris Perry\, Associate Professor\, School of Kinesiology & Health Science York University \nUnderlying mechanisms of Duchenne muscular dystrophy
URL:https://mycrbi.com/event/992/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20200212T100000
DTEND;TZID=America/Toronto:20200212T110000
DTSTAMP:20260510T051153
CREATED:20250313T141650Z
LAST-MODIFIED:20250313T141650Z
UID:990-1581501600-1581505200@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Norberto Guzman\, Chief Scientific Officer Princeton Biochemicals Inc. \nPoint of Care Analytical Techniques
URL:https://mycrbi.com/event/990/
CATEGORIES:Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20200124T100000
DTEND;TZID=America/Toronto:20200124T110000
DTSTAMP:20260510T051153
CREATED:20250313T141314Z
LAST-MODIFIED:20250313T141314Z
UID:988-1579860000-1579863600@mycrbi.com
SUMMARY:
DESCRIPTION:CRBI Seminar – Sergei Manzhos\, Associate Professor School of Materials and Chemical Technology\, Tokyo Institute of Technology \nArtificial Intelligence
URL:https://mycrbi.com/event/988/
CATEGORIES:Seminars
END:VEVENT
END:VCALENDAR