Full Publication Archives by Lab
Diagnostics and Sustainable Mass-Testing
Featured CRBI outputs advancing point-of-care diagnostics, lateral flow testing, and policy frameworks for sustainable population-scale testing.
A policy roadmap for sustainable mass-testing
Health Affairs Scholar, 2025
Krylov SN et al. CRBI-led paper proposing a sustainable mass-testing framework built around scalable manufacturing, real-time data infrastructure, predictive analytics, and sustainable financing.
Addressing Hemolysis-Induced Loss of Sensitivity in Lateral Flow Assay
Analytical Chemistry 97(13): 7352-7358, 2025
Diagnostics-focused paper directly relevant to CRBI's LFIA and point-of-need testing program.
Integrating Advanced Microfluidic Lateral Flow Systems with a Finger-Prick Blood Collection Cartridge
Biosensors and Bioelectronics, 2025
Translational diagnostics paper extending CRBI's mass-testing and point-of-care platform work.
Accuracy, Standards, and Trustworthy Binding/Potency Studies
Featured CRBI outputs focused on trustworthy binding constants, assay reporting, potency measurements, and practical tools for measurement reliability.
Widespread Omission of Aptamer-Target Binding Verification in Aptasensor Development
Submitted, 2026
CRBI-led international manuscript arguing for a mandatory Kd gate for aptasensor development and reporting.
A Roadmap for Reliable Determination of Aptamer-Target Equilibrium Dissociation Constants (Kd)
ACS Sensors 11(2): 779-791, 2026
Community-facing roadmap for solution-based, orthogonally validated aptamer Kd determination.
A Browser-Based Tool for Assessing Accuracy of ITC-Derived Parameters
ChemBioChem 26:e202500194, 2025
Practical tool paper advancing trustworthy ITC-based binding analysis for Kd, Delta H, and n.
Introducing Quantitative Assessment of Michaelis Constant (Km) Accuracy
ChemBioChem 26:e202500660, 2025
Extends CRBI's quantitative-accuracy program from Kd to Km.
Biomolecular Mechanisms in Health, Disease, and Drug Discovery
Featured outputs spanning protein structure, RNA biology, disease mechanisms, nucleic-acid engineering, genome editing, and therapeutic-development-enabling technologies.
High-affinity, structure-validated and selective macrocyclic peptide tools for Huntingtin
PNAS, 2026
Disease-mechanism and chemical-biology paper relevant to target validation and therapeutic discovery.
Evaluation of Low-Field NMR as a PAT Technology for Upstream Bioprocess Monitoring
Pharmaceutical Research, 2026
Collaborative translational paper linking biomolecular characterization to bioprocess monitoring.
Solution characterization of TraW
Structural Dynamics 13:024701, 2026
Protein-structure and dynamics study in a biologically important bacterial transfer system.
TAZ interactome analysis using nanotrap based affinity purification-mass spectrometry
Journal of Cell Science, 2025
Mechanistic paper on protein interaction networks relevant to muscle biology and disease.
RSV enhances translation of virus-resembling AU-rich host transcripts
Virology Journal 22(1):244, 2025
Host-pathogen and RNA-biology paper linked to disease-relevant gene-expression control.
A General Approach to the Transcription and Reverse-Transcription of Xenonucleic Acids
Chemical Science 16:9749-9755, 2025
Nucleic-acid-engineering paper relevant to future therapeutic or diagnostic applications.
Structural analyses of apolipoprotein A-IV polymorphisms Q360H and T347S
Journal of Biological Chemistry 301:108392, 2025
Mechanistic biomolecular study linked directly to disease biology and thrombosis.
Small molecule inhibitors targeting beta-catenin/TCF4 interaction
Hong Kong International Oncology Forum, 2025
Invited talk highlighting therapeutic development in ovarian cancer.
Methods for Applying Prime Editing and Inverse Prime Editing
Methods in Molecular Biology, 2026
Contribution in genome editing and therapeutic-development-enabling technology.
Using biotin pulse labeling to study transcription dynamics
International Conference on Yeast Genetics and Molecular Biology, 2025
International research presentation aligned with the biomolecular-mechanism direction.